Analysis of childhood leukemia mortality trends in Brazil, from 1980 to 2010

Analysis of childhood leukemia mortality trends in Brazil, from 1980 to 2010

Blog Article

OBJECTIVE: Leukemias comprise the most common group of cancers in children and adolescents.Studies conducted in other countries and Brazil have observed a decrease in their mortality.This study aimed to evaluate the trend of mortality from leukemia in children under 19 years of age in Brazil, from 1980 to 2010.

METHODS: This was an ecological study, using retrospective time series data from the Mortality Information System, from 1980 to 2010.Calculations of mortality rates were performed, including gross, gender-specific, and age-based.For trend analysis, linear and semi-log regression models MENOPAUSE were used.

The significance level was 5%.RESULTS: Mortality rates for lymphoid and myeloid leukemias presented a growth trend, with the exception of lymphoid leukemia among children under 4 years of age (percentage decrease: 1.21% annually), while in the sub-group "Other types of leukemia", a downward trend was observed.

Overall, mortality from leukemia tended to increase for boys and girls, especially in the age groups 10-14 years (annual percentage increase of 1.23% for males and 1.28% for females) and 15-19 years (annual percentage increase of 1.

40% for males and 1.62% for females).CONCLUSIONS: The results for leukemia generally corroborate the results of other similar studies.

A detailed analysis by subgroup Utility Boots of leukemia, age, and gender revealed no trends shown in other studies, thus indicating special requirements for each variable in the analysis.